Juno Books is an imprint of Pocket Books, owned by Simon & Schuster that publishes fantasy books with a strong female protagonist. Their main thrust is Urban Fantasy with a female heroine.
from the Juno Books guidelines:
Juno is currently looking for novels from 80,000 to 100,000 words in length. We are interested in fantasy featuring a strong female protagonist set in a contemporary (or a very few years in the future) world quite like ours except for the intersection/transgression of the numinous (that which is “wholly other”) with/upon the mundane. This world can be open (“magic”, the “supernatural” is known to exist) or closed (where “otherness” is concealed from common knowledge).
Rarely does a major publisher openly ask for submissions. Usually they act like they don’t want your book. All of you Nanowrimo people with a novel or two sitting around, now is the time to submit your novel. Even better, they only take email submissions.